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ea0049oc13.5 | Reproduction & Endocrine Disruption | ECE2017

Urinary cadmium excretion is associated with increased synthesis of cortico- and sex steroids in a family-based Swiss population study

Bochud Murielle , Jenny-Burri Judith , Pruijm Menno , Ponte Belen , Guessous Idris , Ehret Georg , Petrovic Dusan , Dudler Vincent , Haldimann Max , Escher Genevieve , Dick Bernhard , Mohaupt Markus , Paccaud Fred , Burnier Michel , Pechere-Bertschi Antoinette , Martin Pierre-Yves , Vogt Bruno , Ackermann Daniel

Background: Cadmium (Cd) is considered as a human carcinogen. A potential intermediate mechanism could be hormone-related by disturbing steroidogenesis in gonads and adrenal glands. We tested whether urinary Cd excretion, as a marker of long-term exposure, is associated with the urinary steroid profile in the general adult population.Methods and Findings: The Swiss Kidney Project on Genes in Hypertension (SKIPOGH) is a multicentric family-based populatio...
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Published by BioScientifica

Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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